Here’s a great tip to save time and effort if you want to install or update your regular (freeware) apps all in one go: try Ninite! Ninite is a free service that offers one simple installer for your selected apps, all in one installer. No questions asked, no hassle, no unwanted adware or spyware.
Looking into App-V but not yet made the leap?
Now might be the time. App-V now supports 64-bit!
Check out the App-V 4.6 Release Q & A (Springboard series blog).
Another recommended reading is the Lazy Admin blog post about real world experiences with App-V.